ITGA8
-
Official Full Name
integrin, alpha 8 -
Overview
Integrin alpha-8 is a protein that in humans is encoded by the ITGA8 gene. -
Synonyms
ITGA8;integrin, alpha 8;integrin alpha-8;Integrin alpha 8;ITGA 8;OTTHUMP00000019207
Recombinant Proteins
- Human
- Zebrafish
- Chicken
- Mouse
- Human Cells
- Mammalian Cells
- HEK293
- E.coli
- Wheat Germ
- Flag
- His
- Avi
- Fc
- GST
- DDK
- Myc
Involved Pathway
ITGA8 involved in several pathways and played different roles in them. We selected most pathways ITGA8 participated on our site, such as PIK-Akt signaling pathway,Focal adhesion,ECM-receptor interaction, which may be useful for your reference. Also, other proteins which involved in the same pathway with ITGA8 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Arrhythmogenic right ventricular cardiomyopathy (ARVC) | SGCA,ITGA2,ATP2A2,ACTN2,ITGA4,EMD,ACTN3,CACNG7,DAG1,CACNB4 |
| Cell adhesion molecules (CAMs) | CADM1B,LRRC4C,NRXN1A,SDC2,CLDN23,HLA-A,PVRL2,HLA-DQB1,SELL,ITGB8 |
| Regulation of Actin Cytoskeleton | GSNB,VCL,RAC3,DIAP3,FGF14,PPP1R12B,MAP2K2A,INS1,VCLA,FGF18A |
| Focal adhesion | BIRC2,PIK3R3,PIK3R2,Reln,BRAF,DIAP1,CCND3,CDC42L2,TESK2,MYL12B |
| PIK-Akt signaling pathway | CRTC2,CCNE1,YWHAE,IFNA16,PCK2,LPAR4,FGF10,FGFR4,FGF19,TLR2 |
| ECM-receptor interaction | CD36,LAMB3,ITGB6,ITGA5,THBS3,COL4A2,GP6,LAMA4,ITGB5,COL27A1A |
| Dilated cardiomyopathy | TGFB2,ITGAV,ACTB,EMD,GNAS,Itga10&Itgb1,CACNG8,TTN,CACNG7,PRKACB |
| Hypertrophic cardiomyopathy (HCM) | TPM1,CACNA2D4,RYR2,CACNG8,CACNG4,PRKAG3,LAMA2,ACTG1,SGCD,ITGA6 |
Protein Function
ITGA8 has several biochemical functions, for example, metal ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ITGA8 itself. We selected most functions ITGA8 had, and list some proteins which have the same functions with ITGA8. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| metal ion binding | CHPT1,SRSF7A,TESK1,BCL11BA,ACSM4,CYP3C4,SMAD4,MKRN4,NR2F6B,MICALL2 |
Interacting Protein
ITGA8 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ITGA8 here. Most of them are supplied by our site. Hope this information will be useful for your research of ITGA8.
Resources
Research Area
IntegrinsFocal Adhesion Proteins in VSMC
Integrins in Focal Adhesions
Basolateral Molecules
Related Services
Related Products
References
- Bakdash, G; Vogelpoel, LTC; et al. Retinoic acid primes human dendritic cells to induce gut-homing, IL-10-producing regulatory T cells. MUCOSAL IMMUNOLOGY 8:265-278(2015).
- Shi, L; Zhang, LC; et al. Expression, purification and renaturation of truncated human integrin beta 1 from inclusion bodies of Escherichia coli. PROTEIN EXPRESSION AND PURIFICATION 107:13-19(2015).
